Sildenafil blockiert die Phosphodiesterase-5 und steigert dadurch die intrazellulären cGMP-Konzentrationen. Die Wirkung setzt innerhalb von 30 bis 60 Minuten ein. Seine Halbwertszeit von vier Stunden macht den Wirkstoff zu einem Präparat mit kurzer Wirkdauer. Der Abbau erfolgt über CYP3A4 und CYP2C9, und die Elimination ist überwiegend biliär. Nebenwirkungen wie Kopfschmerzen und Hautrötungen sind vasodilatationsbedingt. Der Begriff viagra kaufen taucht häufig im Zusammenhang mit dem pharmakologischen Standard dieser Substanzklasse auf.

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    I was a bit hesitant. The last time I installed AntiVirus software, it literally killed my computer.

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    I would recommend this, especially at the current price.
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